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Isosafe Injection

Composition

Each ml contains
Isoflupredone acetate USP – 2 mg
Water for injection IP – 1 ml.

Description

Isosafe is adrenocorticoid enter to cytoplasm and joint to special receptors, the complex enter to cell nucleus and joint to DNA, stimulate to make mRNA and proteins. Glucocorticoid inhibits macrophage response to migration inhibiting factor, sensitization of lymphocytes and cellular response to mediators of inflammation.
The glucocorticoid activity is approximately 50 times that of hydrocortisone and 10 times that of prednisolone and 67 times that of cortisone. The drug use intramuscular and intrasynovial injection, it metabolizes in liver and change to inactive lipids.

Indications

Ketosis, Musculoskeletal disorders: rheumatism, lameness, anorexia, depression, Allergic reaction, Infection, Toxicity & Shock

Dosage

For deep intramuscular and local injection
In initiate treat a high dose Glucocorticoid, has more effect than low dose with repeat in treatment
Cattle
10 – 20 mg I.M, according to the size of the animal and severity of the condition. The dose may be repeated in 24 hours as necessary.
Horses
5 – 20 mg I.M. repeated as necessary. `Intrasynovial injection in synovitis is 5 – 20 mg according to size of local.

Contra-indications

• Should not be use in human.
• When it use in the third months last of pregnancy, induce first signs of parturition, death fetus, inflammation of urinary.

Withdrawal Time

Meat: 5 days
Milk: 3 days

Storage & Warning

Keep closed in a cool and dry place, away from sunlight and safe from children.

Packing

Available in 10ml pack size.

FOR VETERINARY USE ONLY

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