Each ml contains
Isoflupredone acetate USP – 2 mg
Water for injection IP – 1 ml.
Isosafe is adrenocorticoid enter to cytoplasm and joint to special receptors, the complex enter to cell nucleus and joint to DNA, stimulate to make mRNA and proteins. Glucocorticoid inhibits macrophage response to migration inhibiting factor, sensitization of lymphocytes and cellular response to mediators of inflammation.
The glucocorticoid activity is approximately 50 times that of hydrocortisone and 10 times that of prednisolone and 67 times that of cortisone. The drug use intramuscular and intrasynovial injection, it metabolizes in liver and change to inactive lipids.
Ketosis, Musculoskeletal disorders: rheumatism, lameness, anorexia, depression, Allergic reaction, Infection, Toxicity & Shock
For deep intramuscular and local injection
In initiate treat a high dose Glucocorticoid, has more effect than low dose with repeat in treatment
10 – 20 mg I.M, according to the size of the animal and severity of the condition. The dose may be repeated in 24 hours as necessary.
5 – 20 mg I.M. repeated as necessary. `Intrasynovial injection in synovitis is 5 – 20 mg according to size of local.
• Should not be use in human.
• When it use in the third months last of pregnancy, induce first signs of parturition, death fetus, inflammation of urinary.
Meat: 5 days
Milk: 3 days
Storage & Warning
Keep closed in a cool and dry place, away from sunlight and safe from children.
Available in 10ml pack size.