Each bolus contains
- Nimesulide BP 400 mg
- Paracetamol IP 1500 mg
Nimusafe Bolus is a nonsteroidal anti-inflammatory drug (NSAID) with selective cyclo-oxygenase-2 (COX-2) enzyme inhibiting property. It has potent analgesic, anti pyretic and anti-inflammatory activity on oral and rectal administration. By respecting the activity of cyclooxygenase-1 (COX-1), nimesulide possesses a much lower risk for gastro duodenal lesions in comparison to other classical NSAIDs. Unlike nimesulide, paracetamol, another effective analgesic and antipyretic agent without anti-inflammatory activity, is a non-selective COX inhibitor.
- Gynecological disorders like metritis & prolapse
- Upper respiratory inflammation.
- Postoperative therapy.
- Pyrexia of unknown origin.
- As a supportive therapy with antibiotics.
Large animals- 1-2 boluses
Small animals- 1/2 to 1 bolus
Nimesulide with COX-2 selective inhibition prevents the release of prostaglandins which is responsible for inflammation, pain & fever. It does not inhibit COX-1 hence does not interface with the synthesis of beneficial prostaglandins.
Storage & Warning
Keep closed in a cool and dry place, away from sunlight and safe from children.
Available in all pack sizes.