Each ml contains
Ketoprofen USP 100 mg
Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) and cyclooxygenase inhibitor. It is a potent analgesic, antipyretic, and anti-inflammatory. Ketoprofen is most-commonly prescribed for musculoskeletal pain from soft tissue injury, osteoarthritis, or other bone and joint problems. It may be used to reduce or control fevers due to viral or bacterial infections. NSAIDs work by inhibiting the body’s production of prostaglandins, thromboxane, and other inflammatory mediators.
Ketosafe is indicated for the symptomatic treatment of arthritis and osteoarthritis. Off-label uses include the treatment of dental or post-surgical pain. In addition to the above, meloxicam has also been studied in the treatment of neuropathic pain.
- Dental Pain
- Neuropathic pain
- Osteoarthritis (OA)
- Pain, Inflammation
- Post-Operative Pain
- Rheumatoid Arthritis
- In pigs Mastitis-Metritis-Agalactia syndrome
Mechanism of action
Ketoprofen inhibits prostaglandin synthetase (cyclooxygenase 1 and 2) enzymes leading to a decreased synthesis of prostaglandins, which normally mediate painful inflammatory symptoms. As prostaglandins sensitize neuronal pain receptors, inhibition of their synthesis leads to analgesic and inflammatory effects. Meloxicam preferentially inhibits COX-2 enzyme
Meloxicam is an anti-inflammatory, analgesic with antipyretic effects in fever. Prostaglandins are substances that contribute to inflammation. This drug also exerts preferential actions against COX-2, which may reduce the possible gastrointestinal effects of this drug.