TOLSAFE INJECTION

50000 in stock

Description

Composition

Each ml contains 40 mg Tolfenamic acid

Description

Tolfenamic acid, with the formula N-(2-methyl-3-chlorphenyl)-anthranilic acid, is a nonsteroidal anti-inflammatory agent.

Chemical structure

Indications

Being an NSAID, is effective in treating the pain, swelling, arthritis etc

Mechanism of action

Tolfenamic acid inhibits the biosynthesis of prostaglandins, and it also presents inhibitory actions on the prostaglandin receptors. As commonly thought, the mechanism of action of tolfenamic acid is based on the major mechanism of NSAIDs which consists of the inhibition of COX-1 and COX-2 pathways to inhibit prostaglandin secretion and action and thus, to exert its anti-inflammatory and pain-blocking action.

Toxicity

Tolfenamic acid has a relatively low acute toxicity. The metabolites of tolfenamic acid are reported to have an even less important toxicity. Some of the expected toxicity is related to the presence of gastrointestinal effects such as gut ulceration.

Presentation

30 ml

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